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If a child with sickle cell is taking hydroxyurea, do they need to defer live vaccines?

April 26, 2017CELL child defer hydroxyurea live Sickle taking vaccines

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If a child with sickle cell is taking hydroxyurea, do they need to defer live vaccines?

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Hydroxyurea is an antineoplastic agent that is used for some cancers as well as sickle cell disease. It inhibits DNA synthesis and therefore should be considered in the same category as antimetabolites. Defer live vaccines for 3 months following therapy.