Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

I have many equivocal results with IFE on urine samples – can serum FLC assays help?

April 26, 2017assays equivocal FLC help ife results samples serum urine

0

Posted

I have many equivocal results with IFE on urine samples – can serum FLC assays help?

1 Answer

0

Posted

Yes, because low levels of urinary monoclonal FLC (and therefore equivocal results) are usually associated with highly elevated serum FLC levels and abnormal FLC ratio. An equivocal IFE with a normal FLC result can reasonably be interpreted as “no monoclonal protein detected”. An equivocal result with an abnormal FLC result should be used as trigger for further studies.