I have just been told that my prostate cancer has become hormone-refractory and my oncologist suggested that I go on a drug called ketoconazole and hydrocortisone. What are the correct doses?
The starting dose of ketoconazole is 200 milligrams (one tablet) three times daily on an empty stomach. Some doctors believe that it is more effective when taken with vitamin C (or anything acidic, such as coffee or cola), and that if it is tolerated, the dose should be increased slowly to 400 milligrams (two tablets) three times daily, along with 20 milligrams of hydrocortisone orally twice daily. It can, however, work at the lower dosage if not tolerated when the dose is increased.
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