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I have heard that you can be premedicated with steroids and antihistamines to prevent adverse reactions. Does that work?

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I have heard that you can be premedicated with steroids and antihistamines to prevent adverse reactions. Does that work?

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Yes, there has been work that suggests that premedication may reduce the incidence of reactions. The problem is that a program of premedication is a logistical nightmare for any department, and given the somewhat limited benefit, if any, most do not premedicate.

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