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I am taking T3 and feel fine, but my doctor says my thyroid function tests are completely abnormal. What is going on?

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I am taking T3 and feel fine, but my doctor says my thyroid function tests are completely abnormal. What is going on?

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A Free T4 or total T4 is commonly measured to assess the adequacy of thyroid hormone replacement. In patients taking T3, the T4 is often extremely low, since the thyroid gland will often shut off production of T4 in this situation. Furthermore, depending on what time a blood test is done in relationship to ingestion of the T3 tablet, the T3 level may range from low to normal to high. This variability is due in part to the short half life of T3 in our circulation. In such patients, the TSH is generally the best single determinant of whether thyroid hormone replacement is adequate.

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