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I am HER2 positive. Can I receive Avastin® (bevacizumab) with my chemotherapy?

April 26, 2017bevacizumab chemotherapy HER2 positive

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I am HER2 positive. Can I receive Avastin® (bevacizumab) with my chemotherapy?

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If you are HER2 positive, the antibody of choice for you is Herceptin® (trastuzumab). However, if you have previously received trastuzumab and stopped benefiting from it, or if you have a contraindication to trastuzumab—such as abnormal heart function—you can discuss the use of bevacizumab with your oncologist. Bevacizumab, when added to Taxol® (paclitaxel), doubled its ability to shrink tumors and also nearly doubled the time to progression of disease. You should discuss the side effects and risks of bevacizumab with your oncologist and make sure you undergo appropriate testing, such as MRI of the brain to rule out any spread to the brain before you start this therapy.