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I am aware that in the UK the NHS suggests a threshold for biopsy of 4.0ng/ml, yet the IMPACT study is referring patients for biopsy if they have a PSA level of 3.0ng/ml. Why?

April 26, 2017biopsy impact ML NHS study suggests threshold UK

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I am aware that in the UK the NHS suggests a threshold for biopsy of 4.0ng/ml, yet the IMPACT study is referring patients for biopsy if they have a PSA level of 3.0ng/ml. Why?

1 Answer

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PSA is age related (i.e. PSA levels often rise as an individual becomes older), and we are recruiting a relatively young population of men, we have reduced the PSA threshold.