How will vaccine adverse events be handled? What protocols will be followed for actual or claimed serious adverse events?
Prospective vaccinees will be educated about the contraindications to smallpox vaccination in order to minimize serious adverse reactions to the vaccine. A good system to monitor and treat adverse events will be an integral part of this policy, and will be done in close collaboration between the CDC, states, and public health agencies and hospitals. The states will maintain records of people vaccinated and will work with hospitals to set up systems to diagnose, manage, and treat people who experience adverse reactions from the vaccine. This will include rapid access to the primary treatment for most serious adverse events, Vaccinia Immune Globulin (VIG). It is expected that most of the side effects caused by smallpox vaccinations will not require special treatment or therapy. There are two treatments that may help people who have certain serious reactions to the smallpox vaccine. These are: Vaccinia Immune Globulin (VIG) and Cidofovir. Patients receiving these drugs would need to stay
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