How were the protein kinases and phosphatases in this database identified?
The phosphoregulator set was identified as part of the FANTOM2 initiative. The initial paper (Forrest et al. 2003) identified protein kinases and phosphatases by the presence of catalytic domains predicted by Interpro. These proteins were then mapped to the genome and clustered using TribeMCL. This set of protein kinases and phosphatases has now been expanded to include the atypical protein kinases identified by (Caenepeel et al.
