How was the sequencing done? Are there still gaps?
The genome sequence was determined by a whole genome shotgun sequencing strategy supported by clone-based sequencing and a BAC physical map (Adams et al. 2000; Myers et al. 2000; Hoskins et al. 2000). The sequence data set consists of (1) over 3 million sequence reads generated from the ends of 2 kb and 10 kb genomic clones (Celera Genomics); (2) 19,738 sequence reads from the ends of BAC clones (Genoscope); (3) 29 Mb of finished sequence from BAC, P1 and cosmid clones (BDGP-LBNL and EDGP); and (4) draft sequence reads (>= 1.5 X coverage) from 825 BAC and P1 clones spanning 97% of the euchromatic portion of the genome (BDGP sites at LBNL and Baylor College of Medicine). Paired-end sequence data was essential to the correct assembly of the whole genome shotgun data at Celera Genomics; 72% of sequence reads in the whole genome shotgun were in the form of paired-end sequence and provided the information necessary to assemble ordered and oriented sequence contigs. Finishing is being comple
