How was the nationwide increase in cases detected?
In 2006, the Illinois Department of Health contacted CDC to report an increase in AK cases in Illinois that were under investigation by the University of Illinois at Chicago. In January 2007, CDC initiated a retrospective survey of 22 ophthalmology centers nationwide to assess whether cases of AK had been increasing in the United States over the past 8 years. In March 2007, data received from 13 of these centers demonstrated an increase in culture-confirmed cases of AK beginning in 2004 with a wide geographic distribution. On March 16, 2007, CDC initiated a multi-state investigation to look for risk factors associated with this increase in AK cases.
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