How to prevent or reduce adverse reactions to blood transfusion?
Acute hemolytic transfusion reactions are most commonly due to clerical error and mislabeling and this can be prevented with proper guidelines and strict implementation of the guidelines. Febrile non hemolytic transfusion reaction (FNHTR) can be reduced by prior (before transfusion of blood) administration of acetaminophen (commonly known as paracetamol). Allergic transfusion related reactions can be minimized by prior administration of antihistamines, if recipient has history of allergic transfusion reactions. In case of extreme sensitized recipient cellular components such as packed red cells, concentrated platelets can be washed to remove plasma. Transfusion related acute lung injury is most commonly seen if the donor is a multiparous woman and to prevent this, multiparous woman should not be selected for blood donation. Acute hemolytic transfusion reaction occurs most commonly due to mislabeling and clerical errors and to prevent this there should be proper guidelines and followed
