How to Overcome Tarceva Resistance?
Hi All, My father was diag with stage 4 non small cell lung cancer March of 2005. He had 2 rounds of chemo that was successful followed by 2 more rounds that were not. Unfortunately I do not remember which chemo drugs they were My father was then offered Tarceva around July 2005. He had tolerated it well, but he just had a scan on May 31 b/c he has not been feeling well. Well today the results showed that the tumor in the liver has increased in size, which is an indication that he has become resistant to the drug. He has never had any luck with decreasing the size of his lung tumors, but at least the liver tumor has shrunk a little prior to the latest scan. The doctor had told my parents that there are no other drugs out there that would be benefical. I guess the next course of treatment for him is to double the dose of the Tarceva and to monitor it through another scan late June. Just wondering if anyone has become resistant to Tarceva or Iressa for that matter and how it was dealt wi
