How to check the efficiency of adenovirus infection in my target cells?
The Adenovirus has a very broad host range; it can infect human and other mammalian cell lines or primary cells, including dividing and non-dividing cells. There are in fact very few cell lines that cannot be infected. It has been shown that cells of Hematopoietic origin are more resistant to adenovirus infection, and so may need high quantities of viruses to achieve sufficient infection levels as those cells have only limited CAR receptors expressed on cell membrane. For your convenience, we offer some marker adenoviruses, such as Ad-CMV-ß-Gal or AdEGFP to allow you to evaluate infection efficiency in your target cells.
