How the process or formulation conditions are varied to permit formulations of both low-water soluble and high-water soluble compounds?
Our standard formulation procedure consists of 3 different steps: prediction, screening and optimization. During the first step we use our searchable NanoFlow and NanoSAR database to predict which stabilizers would be suitable for the nanonization of active based on its molecule structure or functional groups. There is no significant difference in the procedure whether the active is water soluble or insoluble. The prediction step is followed by the screening where the stabilizers and solvents are selected for the optimization step. In the optimization phase the final nanoformulation is developed with the requested particle size range.
