How soon can the patient expect to see improvement?
In clinical trials significant improvement was observed in many children and adolescents with irritability associated with autism at eight (8) weeks. Irritability was measured using the Aberrant Behavior Checklist (ABC)* * Aberrant Behavior Checklist (ABC): a standardized checklist designed to measure behavioral problems in children with developmental disabilities. The checklist is made up of 5 subscales (Irritability, Lethargy and Social Withdrawal, Stereotypic Behavior, Hyperactivity/Noncompliance, and Inappropriate Speech); higher subscale scores indicate increased symptom severity. The ABC-Irritability (ABC-I) subscale was the primary outcome measure used in the RISPERDAL® clinical trials.
