How soon can Oxycodone be taken for pain after Suboxone?
Suboxone (buprenorphine & naloxone) can stay in your system up to 48 – 72 hours. As long as it’s in your system, the buprenorphine and the oxycodone will be competing with each other for opiate receptors in your brain; thus reducing the effect of oxycodone. Best to wait at least the half life of buprenorphine (20-48 hrs.) before taking the oxy.