How should the CAP (1-84 PTH) and CAP /CIP (1-84/7-84 PTH) values be interpreted?
“CAP ” is the term for 1-84 PTH, which is the hormone responsible for causing classical secondary hyperparathyroidism that gives rise to the high bone turnover condition. “CIP “, on the other hand, denotes the natural antagonist or the hormone which can give rise to the adynamic low bone turnover condition. When CAP (1-84 PTH) appears in great excess compared to CIP (7-84 PTH), then the high bone turnover condition of renal osteodystrophy can be the correct prediction. Conversely, when CIP (7-84 PTH) appears in excess over CAP (1-84 PTH)–(i.e., there is more circulating CIP 7-84 PTH compared to CAP 1-84 PTH or the CAP /CIP ratio is less than one), then the adynamic low bone turnover condition can be the correct prediction. Based on evidence, one may conclude that an untreated patients CAP /CIP ratio value of less than one indicates adynamic low bone turnover. When the CAP /CIP ratio is greater than one, the untreated patient is in a normal or high bone turnover condition. When the CAP
