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How should imipenem-cilastatin be used in the treatment of fever and infection in neutropenic cancer patients?

April 26, 2017cancer fever infection neutropenic Patients treatment Used

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How should imipenem-cilastatin be used in the treatment of fever and infection in neutropenic cancer patients?

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Imipenem-cilastatin (referred to hereafter as imipenem) is administered at different doses as monotherapy or with other agents. Limited comparisons of the alternatives exist. The authors compared the efficacy and safety of several imipenem-containing regimens (ICRs) to determine the appropriate dose and the need for combination therapy.