How should BJP be detected in urine?
Bence-Jones Proteins are normally detected by urine protein electrophoresis. The sensitivity of the protein stain and the total protein concentration dictates whether the BJP needs to be concentrated. The test for adequate sensitivity of the method is that albumin should be visible in all urines studied. Following electrophoresis that show the presence of protein bands, the typing of the light chains of paraproteins is undertaken by immunofixation electrophoresis.
