How serious is a case of infectious mononucleosis?
The symptoms of the disease usually resolve without treatment in one to four months. Sometimes, your spleen or liver may enlarge, and you may have to limit your activity until these organs return to normal size. Heart problems or involvement of the central nervous system occur only rarely. Infectious mononucleosis may cause severe liver failure in males with a special XLP gene. In this rare case, mononucleosis can be fatal.
