How sensitive is the determination of the absolute structure to inaccuracies in the model?
It is fairly insensitive to changes in the structure that only affect the non-anomalous scatterers. In early attempts we have tried to determine the absolute structure of a model refined without hydrogen atoms, and results were still surprisingly discriminative. Errors in the model that concern the anomalously scattering atoms will disrupt the correct absolute structure determination (most likely you will get the result that both absolute structures are equally (un)likely).
