How often does primordial dwarfism occur in humans?
There are over 200 different types of dwarfism, all of which involve bone growth disorders (osteodysplasia) that result in short stature (adult height less than 4 ft. 10 in. tall). Primordial dwarfism is a group of disorders in which growth is proportional but severely delayed, beginning in the womb. This results in some of the smallest people in the world. Meier-Gorlin syndrome Majewski osteodysplastic primordial dwarfism (MOPD) Types I/III and Type II Since these conditions are rare, it is difficult to know how often they occur. It is estimated that about 100 individuals worldwide have been identified as having MOPD Type II. Both males and females of all ethnic backgrounds are affected. Some families have more than one child with MOPD Type II, which suggests that the disorder is inherited in an autosomal recessive pattern. Symptoms The first symptom of primordial dwarfism is the failure of the fetus to grow normally in the womb, a condition called intrauterine growth retardation (IUG
