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The amount of plasma removed from a patient in TPE is based on the plasma volume (PV). Most TPE procedures exchange 1 to 1.5 PV of the patient. The PV is a calculated value, such as: PV = Total Blood Volume x (1.0 – .hematocrit) Total blood volume may be estimated by the use of a Nomogram or by multiplying the weight of a patient by 65 ml/kg.
