How much preliminary data is expected for the PS-OC proposals? What if the preliminary data is demonstrated using systems other than cancer models?
The preliminary data should be sufficient for the reviewers to assess the likelihood of success and the value of the data generated. There should be evidence that the center will be technically capable of generating the proposed data, but it is not expected that full data sets will be available preliminarily. As the RFA states that PS-OCs are expected to “catalyze a fundamentally new understanding of the emergence and behavior of cancer based on a unifying physical-sciences based thematic approach”, it is acceptable to incorporate preliminary data obtained using other model systems in demonstrating the scientific merit of the proposed physical-science approach and suggest the potential impact of the approach in addressing major barriers in cancer processes.
