How might clinical laboratory tests fit into these various scenarios?
Take your pick. It could be as simple as an ELISA, or as complicated as PCR. Or a bit of both. R&D Systems’ Dr. Tsang, also a speaker at the AACC meeting, outlines several methods for measuring cytokines. At the protein level, approaches include: • bioassays, which measure the biologically active molecule. • immunoassays, which detect not only the biologically active molecule but the denatured inactive cytokine and cytokine precursors, and fragments. • functional immunoassays, which can use the extracellular domain of a cytokine receptor, which in turn binds only to the active cytokine. • receptor-binding assays, which are another form of functional assays and which use cell fragments, rather than a living cell, for the binding study. Immunoassays and functional immunoassays are by far the most specific and sensitive, can be done quickly, are cost-effective, and are amenable to automation and high-throughput applications, Dr. Tsang notes. Because immunoassays measure active and inactiv
Related Questions
- Since I perform only a few simple tests in my office, do Clinical Laboratory Improvement Amendments (CLIA) regulations apply to my practice?
- How does the DSGT differ from the usual full-body medical examinations or clinical laboratory tests?
- How might clinical laboratory tests fit into these various scenarios?
