How mandrax (methaqualone) is isolated, identified and determined?
sorry, just have some infos Methaqualone1 is a sedative drug. It is similar in effect to barbiturates, a general CNS depressant. It was used in the 1960s and 1970s as an anxiolytic, for the treatment of insomnia, and as a sedative. Usual effects include relaxation, euphoria, and drowsiness, also reducing heart rate and respiration. Larger doses can bring about depression, muscular miscoordination, and slurred speech. An overdose can cause delirium, convulsions, hypertonia, hyperreflexia, vomiting, renal insufficiency, coma, and death through cardiac or respiratory arrest. It resembles barbiturate poisoning but with increased motor difficulties and a lower incidence of cardiac or respiratory depression. Toxicity is treated with diazepam and sometimes an anticonvulsant. Methaqualone was discovered by the Indian researcher M. L. Gujiral in 1955 during an anti-malaria research program. It was marketed as a sleeping pill during the 1960s under a number of tradenames including Renoval and Me
