How long would it take before telomerase can have a significant medical impact, such as cancer screening and/or telomerase therapy?
Since telomerase is detected in almost all tumors and in some cases early in the development of the cancer, early cancer detection using telomerase may be a promising approach. There are already a number of situations where knowledge of the presence of telomerase may have value in risk stratifying patients into those that are likely to have favorable outcomes and those that are not. In some instances we may actually change the way we treat patients if we had this information. There is a lot of interest in this aspect of early cancer detection. However, we shouldn’t set our hopes up that telomerase will be the unique cancer marker so that every time when we get our cholesterol levels tested that we will also be getting a telomerase assay. While this is certainly a possibility, it is more likely that we will eventually use a panel of cancer markers for this approach. There is a major effort at the National Cancer Institute to establish a series of molecular markers for cancer and it is e
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