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How long will my oligos last and how should I store them?

oligos store
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How long will my oligos last and how should I store them?

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Unmodified oligos are stable molecules and can be used for at least 12 months after purchase when stored at -20°C. For long-term storage, oligos should be stored dry at -20°C. If numerous experiments are planned using the same sequence, aliquot the sample, dry all aliquots, and store at -20°C. If the oligos are stored wet, avoid repeated freeze-thaw cycles as this process can lead to physical degradation of the oligo. Oligos generally last longer in TE than in water. Careful handling is recommended to avoid the possibility contamination with nucleases or bacteria.

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