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How long will I take Herceptin® (trastuzumab) after adjuvant chemotherapy for early-stage breast cancer?

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How long will I take Herceptin® (trastuzumab) after adjuvant chemotherapy for early-stage breast cancer?

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You should be receiving it for a total of 1 year because the only trial comparing 2 years of trastuzumab to 1 year of trastuzumab has not been reported. There is only one small study from Finland indicating that a much shorter duration of trastuzumab (about 9 weeks or so) in addition to chemotherapy may confer the same magnitude of benefit as seen with 1 full year of trastuzumab, but that data is not considered strong enough evidence to outweigh the data from four large randomized trials.

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