How long will a bottle of wine last after it is opened?
After a bottle of wine is opened, the wine is immediately exposed to oxygen which causes spoilage reactions to occur. If an opened bottle with headspace is left out on the counter in your kitchen, the wine’s flavor will start to change and the wine may spoil in a few days. Spoilage does not mean that the wine is harmful to drink; in this context it could mean anything from vinegar to just not “tasting good” anymore.