How long should Zinc and Trientene be used in combination?
In our experience, the combination of zinc and trientine is not necessary beyond the initial four to six month period of removing free copper stores. Zinc maintenance therapy works well for most people thereafter. Obviously, treatment programs and decisions need to be individualized. Nevertheless, I am not aware of compelling data to suggest that there is any need for taking the combination of zinc and trientene long term for the majority of people. Fred Askari, M.D.