How long does Zoloft, Paxil, Lexapro or similar depression drugs take to kick in?
It depends on the individual. My experience is also 1-3 days for some improvement with Lexapro and Wellbutrin, but I respond quickly to medication in general. Unlike eightball, I’ve found SSRIs incredibly helpful if used with awareness. Make sure you have a doctor who is responsive and caring (i.e. returns your calls and follows up on your progress). Good for you for seeking help, and good luck.
The newer ones – Lexapro, Celexa, etc – are faster than the older ones – Prozac, Paxil, Wellbutrin, etc. I only have experience with Lexapro but I’ve found that it kicks in in about a week to 10 days, sometimes even faster. I’ve heard from friends that the older SSRIs can take up to 4 weeks to do anything.
