How long a trial should one give insulin-sensitizing medications before adding ovulation stimulation medications?
A good trial period for insulin-sensitizing medications is 3-6 months. Someone with borderline insulin elevations may require a shorter duration of therapy than a woman with a strikingly high level. If ovulation does not resume after 3-6 months, or pregnancy is not obtained, one might consider adding fertility medications. It may also make sense to re-check fasting glucose and insulin levels to see if the insulin-sensitizing therapy is working or if adjustments in treatment should be made.
