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How likely is a person to have a child with Down syndrome if he/she has a sibling with DS?

April 26, 2017child down syndrome DS likely person sibling

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How likely is a person to have a child with Down syndrome if he/she has a sibling with DS?

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For the vast majority of people, having a sibling with DS does not increase one’s risk of having a child with DS. That’s because 95% of all cases of DS are not inherited. The chromosomal test on the person with DS will show how likely it is to be an inherited case.