How likely are perchlorates to cause cancer?
There are no studies of exposure to perchlorates and cancer in humans. Long-term exposure to perchlorates induced thyroid cancer in rats and mice, but there are reasons to believe that humans are less likely than rodents to develop this type of cancer. The National Academy of Sciences (NAS) concluded that it is unlikely that perchlorates pose a risk of thyroid cancer in humans. Perchlorates have not been classified for carcinogenic effects by the Department of Health and Human Services (DHHS) or the International Agency for Research on Cancer (IARC). The EPA determined that perchlorate is not likely to be carcinogenic to humans, at least at doses below those necessary to alter thyroid hormone homeostasis.