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How is the mutation score calculated for each peak?

calculated mutation peak score
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How is the mutation score calculated for each peak?

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Our mutation score is from the theoretical calculation of signal to noise ratio with the normal distribution. Signal is defined as a peak in the mutation electropherogram and noise is defined as the smaller peaks surrounding the mutation in the electropherogram. Mutation Score = -10 log[erfc(s/n)] of a math function.

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