How is the dose of radioactive iodine selected for thyroid remnant ablation?
The does can vary widely, depending on local institutional preference. Generally, the larger the does given the more successful the extent of remnant ablation. Nevertheless, there are very few randomized studies comparing different doses of radioactive iodine for remnant ablation after surgery. For a recent study comparing 50 mCi vs 100 mCi, see A comparison of 1850 MBq (50 mCi) and 3700 MBq (100 mCi) 131-iodine administered doses for recombinant TSH-stimulated postoperative thyroid remnant ablation in differentiated thyroid cancer. J Clin Endocrinol Metab.
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