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How is the diagnosis of multiple myeloma defined?

defined diagnosis Myeloma
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How is the diagnosis of multiple myeloma defined?

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Three major features to diagnose multiple myeloma (otherwise referred to as myelomatosis) are the presence of paraproteins in serum or urine, increased levels of plasma cells in bone marrow and the destruction of bone either as osteolytic lesions or as extreme osteoporosis.

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