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How is the CAP /CIP ratio value determined?

April 26, 2017cap CIP ratio value

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How is the CAP /CIP ratio value determined?

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Each patient sample is tested with both a unique “intact” PTH assay (called “Total Intact PTH”), that measures both CAP (1-84 PTH) and CIP (7-84 PTH) equally (like total cholesterol measures LDL and HDL equally) and a CAP assay. Then the CAP assay value is subtracted from the “intact” PTH assay value to calculate the CIP (7-84 PTH) value. Finally, the CAP value is divided by the CIP value to calculate the CAP /CIP ratio. (Ref. Monier-Faugere, Malluche, et. al., Kidney International, 2001; 60:1460-1468.