How is so different to the existing sequence feature table used by the main databanks?
The Feature Table is a controlled vocabulary of terms describing sequence features and is used to describe the annotations distributed by the large genome databanks (GenBank, EMBL and DDBJ). It does provide a grouping of its terms for annotation purposes, based on the degree of specificity of the term. For example, CAAT_signal is more specific than promoter and both 5’UTR and mRNA are more specific than precursor_RNA. These relationships between the terms are not formalized, thus the interpretation of them is left to the user to infer, and, more critically, must be hard-coded into software applications. This is in contrast to SO where these relationships are explicitly defined. 5_prime_UTR is part_of a transcript, and mRNA is_a kind of transcript. The terms describing sequence features in SO and SOFA are richer than those of the Feature Table. Most of the terms in the Feature Table map directly to terms in SO, although the term names may have been changed to fit the SO naming conventio
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- How is so different to the existing sequence feature table used by the main databanks?