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How is sickle cell disease inherited?

April 26, 2017CELL disease inherited Sickle

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How is sickle cell disease inherited?

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If both parents have sickle cell trait (AS), then each of their children has a 25% chance of having normal hemoglobin (AA), a 50% chance of having trait (AS), and a 25% chance of having have sickle cell anemia (SS). Other forms of sickle cell disease can occur in children if only one of their parents has sickle trait and the other has thalassemia trait of hemoglobin C trait.