How is Sickle Beta Thalassemia Disease Inherited?
People inherit beta thalassemia from their parents. If one parent has beta thalassemia trait and the other parent has sickle cell trait there is a 25 percent (1 in 4) chance with each pregnancy of having a child with sickle cell (Sβ) disease. Sickle cell disease is a lifelong illness that can result in serious health problems. These are the possible outcomes with each pregnancy.
