How is PET different from other imaging modalities?
While anatomical imaging modalities like CT and MRI are focused on structural anatomy, PET evaluates the chemical and physiological changes related to metabolism. Since metabolic changes occur long before structural damage to tissue is evident, PET allows for the detection of disease that other imaging modalities are incapable of detecting. In many instances, early detection and treatment can have a major impact on the outcome of treatment. Also, a single PET study can scan the entire body. This can be a crucial advantage in many instances, especially in oncology, where additional tumors and the spread of disease are sometimes discovered. The replacement of multiple tests is also of benefit to patients and physicians, as the extent of disease is established faster, with greater confidence and at less cost.