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How is Onko-Sure™ different than a D-dimer test?

April 26, 2017d-dimer different onko-sure™ Test

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How is Onko-Sure™ different than a D-dimer test?

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Unlike Onko-Sure™, D-dimer is not approved for routinely to detecting or monitoring cancers. D-dimer is routinely used in the diagnosis of coagulation disorders such as: DIC (Disseminated Intravascular Coagulation), DVT (Deep Vein Thrombosis), PE (Pulmonary Embolism), and Sickle-cell Anemia. Unlike Onko-Sure™. most D-dimer tests are monoclonal antibody based and many are used in a Latex Agglutination (LA) based-assay with single threshold determination. In contrast, Onko-Sure™ is a polyclonal ELISA-based quantitative FDP assay. Onko-Sure™ detects all of the breakdown products of Fibrin and Fibrinogen, including a unique “IPDP” cancer-related breakdown product. D-dimer values alone would greatly under estimate cancer and miss some altogether. For a more detailed description of the importance of monitoring all of the breakdown products for the detection and monitoring of cancer, refer to Figure 2 below.