How is multiple myeloma diagnosed?
Multiple myeloma may be found as part of routine blood or urine tests that may show the presence of an abnormal myeloma protein called monoclonal (M) protein. This protein is also sometimes called Bence Jones protein. Bone X-rays may show holes in the bone called lytic lesions. After blood tests and X-rays, the diagnosis is confirmed by testing the bone marrow during a bone marrow aspiration and biopsy, to check on the presence of plasma cells. After multiple myeloma is diagnosed, the doctor will need to know the extent and characteristics of the myeloma cells to prescribe the best treatment. Chromosome studies should be done on the bone marrow sample taken during the bone marrow aspiration.
