How is mitral valve disease inherited?
Although the pattern of inheritance has not been identified, it is agreed that there is a genetic basis for the early development of mitral valve disease. What breeds are affected by mitral valve disease? There is a relatively high incidence of early development of mitral valve disease in the cavalier King Charles spaniel, Cairn terrier, miniature poodle, and bull terrrier (particularly in the United Kingdom). It is also seen, not as commonly, in the miniature pinscher, toy and standard poodle, whippet, chihuahua, Pekinese, dachshund, beagle, papillon, great Dane, and German shepherd. In general, small breeds are most often affected. Some studies show a greater incidence in males than in females. For many breeds and many disorders, the studies to determine the mode of inheritance or the frequency in the breed have not been carried out, or are inconclusive. We have listed breeds for which there is a general consensus among those investigating in this field and among veterinary practitio
