How is it possible to perform a placebo controlled study in TMS trials?
Researchers have developed criteria for controlled studies using sham equipment and placebo stimulation methodology. They recognize the need to avoid stimulation of the cortex while providing the subject with the illusion of stimulation by creating noises and scalp sensations which would be felt under actual conditions, while pretending to use a TMS coil. There are many different sham coils available which allow for studies to be ran with a control condition, which is very important in proving the effects of TMS.