How is GERD, with or without Barretts esophagus treated?
Medical (non-surgical) therapy The medical treatments for the symptoms of Barrett’s esophagus are the same as those for GERD. The suppression of acid is the backbone of treatment for GERD. For mild reflux symptoms, over the counter medications are commonly used, ranging from antacids to low doses of drugs called H-2 receptor antagonists or H2 blockers. Examples of over the counter H2 blockers are cimetidine (Tagamet) and famotidine (Pepcid). For more persistent symptoms, higher (prescription-strength) doses of the H-2 receptor antagonist drugs may be used, for example: • cimetidine (Tagamet), • famotidine (Pepcid), • ranitidine (Zantac), and • nizatidine (Axid). However, for persistent symptoms requiring maintenance (ongoing) therapy or for complicated GERD with strictures or bleeding, proton pump inhibitors (PPIs) are used. Examples of PPIs are: • omeprazole (Prilosec, Zegerid), • lansoprazole (Prevacid), • pantoprazole (Protonix), • rabeprazole (Aciphex), and • esomeprazole (Nexium).