How is diphtheria diagnosed?
The diagnosis of diphtheria is confirmed by isolation of the bacterium Corynebacterium diphtheriae. Diagnostic tests to isolate the bacterium involve obtaining cultures from the nose and throat in any individual suspected of having diphtheria, as well as their close contacts. It is also important to determine whether or not the isolate is capable of producing diphtheria toxin, and this can be accomplished by testing in specialized laboratories. Finally, determining the patient’s antibody levels to diphtheria toxin can also be helpful for evaluating the probability of the diagnosis of diphtheria and the potential for severe illness. Other tests, such as ECG, imaging studies, and blood work can also help assess the extent of involvement of the disease. What is the treatment for diphtheria? If diphtheria is suspected in a patient, prompt treatment should be undertaken even before confirmatory lab results are available. Diphtheria antitoxin is the mainstay of therapy. It neutralizes circul